How much chemotherapy is not an obese woman need? Typically an obese woman with breast cancer will receive chemotherapy dose reduce as they battle breast cancer.
Back in June 2005, a study published in the Archives of Internal Medicine concluded that obese women should receive chemotherapy based on their actual women, and not the reduced amount as a standard practice.
And now again a study presented at the August 2005 issue of the Lancet claims that doctors should not reduce chemotherapy doses for obese women when no receptors for the hormone estrogen have been found in breast cancer cells. This type of cancer is called estrogen-receptor negative.
Clinicians often reduce chemotherapy doses for obese patients because of concerns about how to react to patient care and affect their overall health.
Back in June 2005, a study published in the Archives of Internal Medicine concluded that obese women should receive chemotherapy based on their actual women, and not the reduced amount as a standard practice.
And now again a study presented at the August 2005 issue of the Lancet claims that doctors should not reduce chemotherapy doses for obese women when no receptors for the hormone estrogen have been found in breast cancer cells. This type of cancer is called estrogen-receptor negative.
Clinicians often reduce chemotherapy doses for obese patients because of concerns about how to react to patient care and affect their overall health.
According to research director Marco Colleoni of the European Institute of Oncology, Italy, and his colleagues, reducing the first course of chemotherapy for obese patients with estrogen receptor negative breast cancer prove "detrimental".
Colleoni and his team looked at the relationship between body mass index (BMI), reduction in chemotherapy dose, estrogen receptor expression, and the results for pre-menopausal women with breast cancer by examining data from four randomized trials.
They found that 97 of 249 obese patients received less than 85 f protocol specified dose during the first chemotherapy compared with patients with normal and high BMI.
Obese patients with estrogen receptor negative disease who received 85 r over the first protocol specified dose significantly better disease-free survival and overall survival than those who received less than 85 f dose is usually recommended.
However, obese patients with estrogen receptor positive breast cancer who had reduced doses of chemotherapy did not have significant differences in their results compared with those given the recommended dose of chemotherapy.
And contrary to popular practice, the researchers also noticed that obese patients initially treated with chemotherapy protocol dose not have more toxicity than patients who received a reduced dose.
Dr Marco Colleoni concluded that, "Our findings suggest that for women with ER-absent or ER-low, chemotherapy dose reduction should be avoided."
Message for obese women cope with cancer is to be aware of the risks and rights. Ask your doctor to recommend him a low dose of chemotherapy for you based on your weight and ask why.
They found that 97 of 249 obese patients received less than 85 f protocol specified dose during the first chemotherapy compared with patients with normal and high BMI.
Obese patients with estrogen receptor negative disease who received 85 r over the first protocol specified dose significantly better disease-free survival and overall survival than those who received less than 85 f dose is usually recommended.
However, obese patients with estrogen receptor positive breast cancer who had reduced doses of chemotherapy did not have significant differences in their results compared with those given the recommended dose of chemotherapy.
And contrary to popular practice, the researchers also noticed that obese patients initially treated with chemotherapy protocol dose not have more toxicity than patients who received a reduced dose.
Dr Marco Colleoni concluded that, "Our findings suggest that for women with ER-absent or ER-low, chemotherapy dose reduction should be avoided."
Message for obese women cope with cancer is to be aware of the risks and rights. Ask your doctor to recommend him a low dose of chemotherapy for you based on your weight and ask why.
Tag :
Health
0 Komentar untuk "Chemotherapy for obese woman"